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Epidemiological drug monitoring programs, such as the Boston Collaborative Drug Surveillance Program, provide a clear and reasonably complete picture of adverse drug reactions.
The findings of the Boston Collaborative Drug Surveillance Program on the toxicity of drugs are summarized, and the methodologies of this and other epidemiological drug monitoring programs are defended. It is concluded that the currently available data on adverse drug reactions provide a reasonably complete and clear picture of the "ADR problem".
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Russell R. Miller (1977) studied this question.
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