Tracing the origins of life: TNA (see picture) shows base pairing which is similar to that of pentose-based RNA in regard to specificity, strand orientation, and pairing strength. TNA hybridizes with the natural nucleic acids RNA and DNA and is able to form hairpin structures. The potential of TNA as a genetic precursor of RNA is discussed.
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Piet Herdewijn (2001) studied this question.