April 1, 1985European Journal of Biochemistry

The widespread distribution of α‐N‐trimethylalanine as the N‐terminal amino acid of light chains from vertebrate striated muscle myosins

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Population

Bovine cardiac alkali light chain, rabbit fast muscle LC2 light chain, and various vertebrate and…

Design

Preclinical

Authors

GHGillian D. HenryTufts University ITIan P. TrayerUniversity of Birmingham SBSusan BrewerStanford University

Discussion

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Implication

Me3Ala marks specific vertebrate striated light chains; leaves open its role in actin interactions or muscle disease.

Structured PICO

Population

Bovine cardiac alkali light chain, rabbit fast muscle LC2 light chain, and various vertebrate and invertebrate muscle light chains

Intervention

Chemical, electrophoretic, and 1H-NMR spectroscopy analysis

Outcome

Identification and distribution of alpha-N-trimethylalanine (Me3Ala) as the N-terminal amino acidsurrogate

The study identifies alpha-N-trimethylalanine as a general feature of the N-terminal amino acid in specific vertebrate striated muscle myosin light chains, with implications for actin interaction.

Cite This Study

Henry et al. (1985) studied this question.

synapsesocial.com/papers/6a6f42cf660549caf2c3d294 https://doi.org/10.1111/j.1432-1033.1985.tb08809.x

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The widespread distribution of α‐N‐trimethylalanine as the N‐terminal amino acid of light chains from vertebrate striated muscle myosins

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The widespread distribution of α‐N‐trimethylalanine as the N‐terminal amino acid of light chains from vertebrate striated muscle myosins

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider