Clinical review demonstrates elevated low-density lipoprotein cholesterol increases coronary risk in adults with hyperlipidemia, indicating lipid-lowering therapy prevents cardiovascular events.
INCREASED concentrations in plasma of certain lipoproteins or of plasma lipids, which indirectly reflect lipoprotein concentration, are associated with an increased risk of atherosclerotic heart and peripheral vascular disease.1 2 3 Risk of heart attack is related to the plasma concentration of low-density or β-lipoproteins (LDL) and, therefore, to the plasma cholesterol concentration, since the cholesterol carried by LDL usually accounts for two thirds or more of the total plasma cholesterol.3 4 5 Coronary disease risk may also be related to the concentration of very-low-density or pre-β-lipoproteins (VLDL), although the correlation is less convincing than that of LDL.1 2 3,6In addition to its association with . . .
No takes yet. Share an insight, caveat, or question.
Lees et al. (1971) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: