Key result
The STEMI Systems Accelerator program increased guideline-directed reperfusion for men (e.g., 58.7% to 62.1% for direct presenters; P=0.01) and white patients, but not for female or black patients.
Why the study?
Does the STEMI Systems Accelerator program reduce reperfusion disparities between female vs male and black vs white patients presenting with STEMI?
Observational (n=23,809)
Yes
Does the STEMI Systems Accelerator program reduce reperfusion disparities between female vs male and black vs white patients presenting with STEMI?
Regional systems of care improvements for STEMI increased timely reperfusion for male and white patients but failed to reduce disparities for female and black patients.
Caution against assuming systems programs close disparities; challenges equitable impact assumptions and extends targeted equity research.
Background The American Heart Association Mission: Lifeline STEMI ( ST ‐segment–elevation myocardial infarction) Systems Accelerator program, conducted in 16 regions across the United States to improve key care processes, resulted in more patients being treated within national guideline goals (time from first medical contact to device: <90 minutes for direct presenters to hospitals capable of performing percutaneous coronary intervention; <120 minutes for transfers). We examined whether the effort reduced reperfusion disparities in the proportions of female versus male and black versus white patients. Methods and Results In total, 23 809 patients (29.3% female, 82.3% white, and 10.7% black) presented with acute STEMI between July 2012 and March 2014. Change in the proportion of patients treated within guideline goals was compared between sex and race subgroups for patients presenting directly to hospitals capable of performing percutaneous coronary intervention (n=18 267) and patients requiring transfer (n=5542). The intervention was associated with an increase in the proportion of men treated within guideline goals that presented directly (58.7–62.1%, P =0.01) or were transferred (43.3–50.7%, P <0.01). An increase was also seen among white patients who presented directly (57.7–59.9%, P =0.02) or were transferred (43.9–48.8%, P <0.01). There was no change in the proportion of female or black patients treated within guideline goals, including both those presenting directly and transferred. Conclusion The STEMI Systems Accelerator project was associated with an increase in the proportion of patients meeting guideline reperfusion targets for male and white patients but not for female or black patients. Efforts to organize systems of STEMI care should implement additional processes targeting barriers to timely reperfusion among female and black patients.
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Hinohara et al. (2017) conducted an observational in ST-segment-elevation myocardial infarction (n=23,809). Mission: Lifeline STEMI Systems Accelerator program vs. Female and black patients (subgroup comparison) was evaluated on Proportion of patients treated within national guideline goals (time from first medical contact to device <90 minutes for direct presenters, <120 minutes for transfers). The STEMI Systems Accelerator program increased guideline-directed reperfusion for men (e.g., 58.7% to 62.1% for direct presenters; P=0.01) and white patients, but not for female or black patients.
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