Key result
This review outlines the cellular and molecular mechanisms of smooth muscle cell hypertrophy, proliferation, migration, and apoptosis involved in vascular remodeling during pulmonary hypertension.
This review summarizes the cellular and molecular mechanisms driving pulmonary artery smooth muscle cell remodeling in pulmonary hypertension.
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No immediate change to pulmonary hypertension management; leaves open targeted interventions against smooth muscle cell remodeling.
Tajsic et al. (2011) conducted a review in Pulmonary hypertension. This review outlines the cellular and molecular mechanisms of smooth muscle cell hypertrophy, proliferation, migration, and apoptosis involved in vascular remodeling during pulmonary hypertension.
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