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July 1, 1987Journal of Clinical InvestigationOpen Access

Mechanisms of thrombocytopenia in chronic autoimmune thrombocytopenic purpura. Evidence of both impaired platelet production and increased platelet clearance.

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Authors

PBPenny BallemUniversity of British ColumbiaGSGerald M. SegalOregon Health & Science UniversityJSJon StrattonUniversity of South Australia

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Ballem et al. (1987) studied this question.

synapsesocial.com/papers/6a6f4d6aa528af2d65c2ecbbhttps://doi.org/10.1172/jci113060
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The effects of acute thrombocytopenia on megakaryocyte-CFC and granulocyte-macrophage-CFC in mice: studies of bone marrow and spleen1980 · 63 citations
  2. 2Kinetics and sites of destruction of 111indium‐oxine‐labeled platelets in idiopathic thrombocytopenic purpura: A quantitative study1982 · 87 citations
  3. 3Platelet Survival and Platelet Production in Idiopathic Thrombocytopenic Purpura (ITP)1974 · 127 citations
  4. 4The relation of thrombokinetics to bone marrow megakaryocytes in idiopathic thrombocytopenic purpura (ITP)1975 · 88 citations