Key result
Lactate values measured during mild hypothermia in patients with cardiac arrest were related to in-ICCU death, which occurred in 45.5% of the cohort.
Why the study?
Do lactate values measured during mild hypothermia predict in-ICCU death in patients with cardiac arrest?
Observational (n=33)
Do lactate values measured during mild hypothermia predict in-ICCU death in patients with cardiac arrest?
Lactate values measured during mild hypothermia hold prognostic value for predicting in-ICCU mortality in cardiac arrest patients.
Lactate during mild hypothermia may aid risk stratification post-arrest; leaves open prospective validation before guiding care.
BACKGROUND AND METHODS: The present investigation was aimed at assessing the dynamic behaviour of lactate values during hypothermia in 33 patients with cardiac arrest. RESULTS: Fifteen patients died during intensive care stay (15/33, 45.5%). When compared to survivors, they were older (survivors 50.7 ± 14.7 vs. non-survivors 70.1 ± 10.4 years, p<0.001) and exhibited a significantly higher APACHE score (survivors 21.9 ± 3.9 vs. non-survivors 27.5 ± 4.6, p<0.001). A higher incidence of non-shockable rhythms was observed in non-survivors (p=0.026) who showed a longer collapse-recovery of spontaneous circulation time (p=0.01). During hypothermia, lactate values showed a progressive and significant decrease despite no significant change in mean arterial pressure and central venous pressure (i.e. independently of blood pressure values and volaemia). Lactate values when measured during hypothermia were related to in-intensive cardiac care unit (in-ICCU) death. CONCLUSION: In our series, lactate values measured during hypothermia hold a prognostic role in these patients since they are related to in-ICCU death.
No takes yet. Share an insight, caveat, or question.
Lazzeri et al. (2013) conducted an observational in Cardiac arrest (n=33). Lactate values was evaluated on in-ICCU death. Lactate values measured during mild hypothermia in patients with cardiac arrest were related to in-ICCU death, which occurred in 45.5% of the cohort.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: