Bio-signal recording is vital for human condition monitoring and early disease diagnosis. An electrode is a biosensor for bio-signal collection. The conventional wet electrode is not suitable for long-term bio-signal recording owing to the gradual drying of the electrolytic gel and increase in the electrode-skin interface impedance. Microneedle array electrode is a dry electrode that can painlessly pierce skin, form a contact interface between the microneedles and skin tissue, eliminate the high impedance of stratum corneum, weaken the motion artifact, and accurately record bio-signals without skin preparation and application of electrolytic gel. This review focuses on the recently developed fabrication techniques, the mechanical performance, and bio-signal recording performance of microneedle array electrode. The microneedle array electrode is a potential electrode for long-term bio-signal recording, although progress is required in terms of safety and scaled-up manufacture.
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Ren et al. (2019) studied this question.
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