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Base discrimination: A nanocarbon film electrode exhibits sufficiently high activity to obtain sharp, quantitative peaks for all the bases in an oligonucleotide. This property allows the label-free electrochemical analysis of single-nucleotide polymorphisms (SNPs) through the discrimination of single-base differences solely by using electrochemical oxidation (see picture; ssDNA=single-strand DNA).
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Kato et al. (2008) studied this question.
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