SUMMARY Pure calcium deficiency produces osteoporosis, or bone atrophy, in rats, while vitamin D deficiency as well as calcium deficiency leads to osteomalacia, or thin bones with wide osteoid seams. The retention of a dose of strontium in the osteoporotic rats is greater than normal, and this indicates rapid bone formation. The immediate cause of the bone thinning must therefore be an increase in the rate of bone resorption, contrary to the classical concepts of osteoporosis.
No takes yet. Share an insight, caveat, or question.
Harrison et al. (1960) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: