An Assessment by Competition Hybridization of the Sequence Homology between the RNAs of the Seven Serotypes of FMDV

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Structured PICO

Population

RNAs of the seven serotypes of foot-and-mouth disease virus (FMDV)

Intervention

Competition hybridization

Outcome

Sequence homologysurrogate

The study demonstrates significant sequence homology within European/Asia I and SAT groups of FMDV, but much lower homology between these two groups.

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Informs FMDV vaccine strain selection for distinct serotype groups; leaves open cross-protection efficacy between European/Asia I and SAT viruses.

Robson et al. (1977) studied this question.

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Informs FMDV vaccine strain selection for distinct serotype groups; leaves open cross-protection efficacy between European/Asia I and SAT viruses.