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July 27, 2023Veterinary SciencesOpen Access

A Newly Emerging Serotype A Strain in Foot-and-Mouth Disease Virus with Higher Severity and Mortality in Buffalo than in Cattle Calves in North Egypt

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Key result

The newly emerging FMDV serotype A strain caused higher peracute mortality in buffalo calves (25.7%; 95% CI: 13-43) than in cattle calves (8.6%; 95% CI: 2-24).

Why the study?

A severe foot-and-mouth disease epidemic caused significant animal losses even in vaccinated farms, motivating investigation into the newly emerging strain and its effect on buffalo and cattle calves.

Population

70 cattle and buffalo calves in a single infected farm in Beheira province

Comparison

Egyptian water buffalo calves vs cattle calves

Authors

SMSamy MetwallyTokyo University of AgricultureNBNabil BkearDamanhour UniversityYBYassien BadrDamanhour University

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Implication

Alerts to emerging FMDV in vaccinated Egyptian farms; leaves open targeted surveillance and vaccine updates for buffalo.

Study Design

Type

Observational (n=70)

Multicenter

No

Structured PICO

P
Population
70 cattle and buffalo calves in a single infected farm in Egypt, evaluated for clinical severity and mortality from a newly emerging FMDV serotype A strain.
E
Exposure
Infection with newly emerging FMDV serotype A (Euro-SA topotype)
C
Comparator
Comparison between buffalo and cattle calves
O
Outcome
Mortality and clinical signshard clinical

Main Result

Absolute Event Rate: 25.7% vs 8.6%

A newly emerging FMDV serotype A strain in Egypt causes more severe disease and higher mortality in buffalo calves compared to cattle calves.

Cite This Study

Metwally et al. (2023) conducted an observational in Foot-and-mouth disease (n=70). FMDV serotype A infection in buffalo calves vs. FMDV serotype A infection in cattle calves was evaluated on Peracute mortalities. The newly emerging FMDV serotype A strain caused higher peracute mortality in buffalo calves (25.7%; 95% CI: 13-43) than in cattle calves (8.6%; 95% CI: 2-24).

synapsesocial.com/papers/6a6f570375498292b708bbc7https://doi.org/10.3390/vetsci10080488
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Pathological and Molecular Investigations on Foot and Mouth Virus Outbreaks Among Cattle Herds in Dakahlia Governorate, Egypt2016 · 6 citations
  2. 2Molecular detection and phylogenetic analysis of newly emerging foot-and-mouth disease virus type A, Lineage EURO-SA in Egypt in 20222022 · 25 citations
  3. 3MOLECULAR STUDY OF FMD INFECTED EGYPTIAN BUFFALO CALVES WITH REFERENCE TO ELECTROCARDIOGRAPHY AND CARDIAC BIOMARKERS AS PROGNOSTIC TOOLS2018 · 1 citations
  4. 4Detection and identification of Foot and Mouth disease virus serotypes in Assiut governorate, Egypt2017 · 11 citations
  5. 5Outbreaks of Foot‐and‐Mouth Disease in Libya and Saudi Arabia During 2013 Due to an Exotic O/ ME ‐ SA /Ind‐2001 Lineage Virus2014 · 58 citations