Key result
Experimental infection of yaks with FMDV demonstrated that 3 out of 5 animals maintained a carrier status for up to 8 months, accompanied by persistently high antibody levels.
Why the study?
Does experimental infection with FMDV O/Akesu/58 lead to persistent carrier status in Bos grunniens yaks?
Does experimental infection with FMDV O/Akesu/58 lead to persistent carrier status in Bos grunniens yaks?
Bos grunniens yaks can maintain a carrier status for foot-and-mouth disease virus for at least 8 months post-infection, accompanied by high antibody levels and viral gene mutations.
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Suggests yaks as FMDV carriers; hypothesis-generating for control in endemic livestock regions.
Chang et al. (2013) studied Foot-and-mouth disease (n=5). FMDV O/Akesu/58 inoculation was evaluated on FMDV carrier status (virus detection in OP fluids by RT-PCR and CPE). Experimental infection of yaks with FMDV demonstrated that 3 out of 5 animals maintained a carrier status for up to 8 months, accompanied by persistently high antibody levels.
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