Why the study?
Although hypertension prevalence is rising rapidly worldwide, its precise causes remain unclear, prompting investigation into the role of abnormal biological rhythms and emerging treatment strategies.
Circadian rhythm disturbances are mechanistically linked to the development of hypertension, suggesting that chronotherapy, melatonin supplementation, and autonomic modulation may be valuable therapeutic strategies.
According to the largest survey of its kind to date, since 1990, the number of 30-to 79-year-olds with hypertension has increased rapidly from 650 million to 1.28 billion. Although this number is rising rapidly, no one knows what causes blood pressure to rise. The cause of hypertension is still unclear. The factors that contribute to elevated blood pressure are numerous and confusing. Studies have shown that abnormal biological rhythms can lead to hypertension. One of the key factors contributing to elevated blood pressure is an abnormal biorhythm. It has also been shown that abnormal biological rhythms can lead to hypertension. The nervous system, the renin-angiotensin-aldosterone pathway and melatonin secretion from the pineal gland may all be affected by circadian rhythm problems, which in turn affects glucocorticoid-mediated hypertension, and thus the development and progression of hypertension. The current intervention of it mainly based on pharmacological therapy, supplemented by improvement of lifestyle habits. Several new strategies for the treatment of hypertension have emerged in recent years. For example, acupuncture needle treatment, melatonin promotion treatment, RDN treatment hair etc. This study will present these methods and experiments to draw conclusions.
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Yinuo Cai (2023) conducted a review in Hypertension. Circadian rhythm regulation (melatonin, chronotherapy, acupuncture, renal denervation) was evaluated.
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