February 9, 2004Circulation
Short-Term Statin Therapy and Cardiac Function and Symptoms in Patients With Idiopathic Dilated Cardiomyopathy
Why the study?
Does short-term statin therapy improve left ventricular ejection fraction and myocardial blood flow reserve in patients with idiopathic dilated cardiomyopathy?
Population
Patients with idiopathic dilated cardiomyopathy (IDC)
Design
Editorial
Authors
Discussion
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Member takes
Implication
This letter proposes that statin-induced improvements in myocardial blood flow reserve may explain the observed increase in LVEF in patients with idiopathic dilated cardiomyopathy.
Structured PICO
Does short-term statin therapy improve left ventricular ejection fraction and myocardial blood flow reserve in patients with idiopathic dilated cardiomyopathy?
P
Population
Patients with idiopathic dilated cardiomyopathy (IDC)
I
Intervention
Short-term statin therapy (simvastatin)
O
Outcome
Left ventricular ejection fraction (LVEF)surrogate
This letter proposes that statin-induced improvements in myocardial blood flow reserve may explain the observed increase in LVEF in patients with idiopathic dilated cardiomyopathy.
Cite This Study
Harst et al. (2004) studied this question.