Population
Children with acute respiratory infections (ARIs) in Yamagata, Japan (4,107 nasopharyngeal specimens)
Design
Cohort
Follow-up
2 years (2004-2005)
Authors
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Supports year-round pediatric ARI surveillance; leaves open whether modified cell culture improves routine diagnostic yield.
A modified microplate method using multiple cell lines successfully isolated a wide range of respiratory viruses from children with ARIs across all seasons.
Mizuta et al. (2008) studied this question.
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