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Salicylate inhibits rabbit muscle lactate dehydrogenase, horse liver alcohol dehydrogenase, pig heart malate dehydrogenase and pig heart isocitrate dehydrogenase in vitro. The inhibitions are reversible, involving competition with nad, nadh2 or nadp. The results are discussed with reference to some of the in vivo actions of the drug.
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Dawkins et al. (1967) studied this question.
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