Determination of bisphenol A in foods as 2,2-bis-(4-(isopropoxycarbonyloxy)phenyl)propane by gas chromatography/mass spectrometry

A procedure has been developed for the determination of bisphenol A ( BPA ) in foods by gas chromatography/mass spectrometry as 2,2-bis-(4-(isopropoxycarbonyloxy)phenyl)propane formed in the reaction with isopropyl chloroformate. Optimal conditions have been found for BPA derivatization, providing its quantitative conversion into diether derivative in aqueous media. The concentration of BPA has been determined in some samples of canned foods and beverages (from 2.15 to 42.91 ng/g). The detection limit is 0.05–0.1 ng/g.