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Illegitimate recombination is defined to be a recombi-nation between nonhomologous regions or very short homologous regions of DNA (see Franklin 1971; Weis-berg and Adhya 1977). In Escherichia coli, various kinds of illegitimate recombination have been known, includ-ing deletion, duplication, substitution, insertion, a d transducing phage formation. Transposition of transpo-sons (Tn) and insertion sequence (IS) elements may also be included in this classification. These illegitimate re-combinations and transpositions take place indepen-dently ofE. coli recA function, which mediates a general recombination between long homologous regions
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Ikeda et al. (1981) studied this question.
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