Why the study?
Sapovirus is an important cause of acute gastroenteritis in children under 5 years old in lower-income communities, and this study aimed to identify circulating genotypes in the Amazon region.
What sapovirus genotypes are circulating in children in the Northwest Amazon region?
What sapovirus genotypes are circulating in children in the Northwest Amazon region?
The GIV genotype is the most prevalent sapovirus genotype among children in the Northwest Amazon region, with unique strains possibly introduced via tourism.
Sapovirus is an important etiological agent of acute gastroenteritis (AGE), mainly in children under 5 years old living in lower-income communities. Eighteen identified sapovirus genotypes have been observed to infect humans. The aim of this study was to identify sapovirus genotypes circulating in the Amazon region. Twenty-eight samples were successfully genotyped using partial sequencing of the capsid gene. The genotypes identified were GI.1 (n = 3), GI.2 (n = 7), GII.1 (n = 1), GII.2 (n = 1), GII.3 (n = 5), GII.5 (n = 1), and GIV.1 (n = 10). The GIV genotype was the most detected genotype (35.7%, 10/28). The phylogenetic analysis identified sapovirus genotypes that had no similarity with other strains reported from Brazil, indicating that these genotypes may have entered the Amazon region via intense tourism in the Amazon rainforest. No association between histo-blood group antigen expression and sapovirus infection was observed.
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Moraes et al. (2021) studied this question.
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