Key result
In a birth cohort of 100 children followed to age 2, 82% experienced sapovirus infection, with genogroup GI more frequently associated with symptomatic illness (OR 3.1; 95% CI 1.3-7.4).
Population
100 children randomly selected from a community-based birth cohort study in Peru, followed up to age 2 years.
Design
Cohort
Follow-up
up to age 2 years
Authors
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Sapovirus drives substantial early childhood diarrhea burden; leaves open questions on genotype-specific immunity and prevention.
Cohort (n=100)
Odds Ratio: 3.1 (95% CI 1.3–7.4)
Sapovirus is frequently detected in children with acute gastroenteritis during the first 2 years of life, with serial infections by multiple genotypes suggesting genotype-specific immunity.
Sánchez et al. (2017) conducted a cohort in Sapovirus infection (n=100). Sapovirus genogroup GI infection vs. Other genogroups was evaluated on Symptomatic infection (OR 3.1, 95% CI 1.3-7.4). In a birth cohort of 100 children followed to age 2, 82% experienced sapovirus infection, with genogroup GI more frequently associated with symptomatic illness (OR 3.1; 95% CI 1.3-7.4).
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