August 29, 2011European Heart Journal
Myocardial infarction and other co-morbidities in patients with chronic obstructive pulmonary disease: a Danish Nationwide Study of 7.4 million individuals
Why the study?
Is chronic obstructive pulmonary disease associated with an increased risk of myocardial infarction and other co-morbidities?
Population
7.4 million individuals from the entire Danish population from 1980 through 2006, including 313,958 with…
Comparison
Chronic obstructive pulmonary disease diagnosis vs Controls without chronic obstructive pulmonary…
Design
Cohort
Follow-up
1980 through 2006 (140 million person-years)
Authors
Discussion
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Member takes
Implication
COPD was associated with higher MI and comorbidity risks; extends prior cohorts but leaves causal effects and management changes open.
Structured PICO
Is chronic obstructive pulmonary disease associated with an increased risk of myocardial infarction and other co-morbidities?
P
Population
7.4 million individuals from the entire Danish population from 1980 through 2006, including 313,958 with ever-diagnosed chronic obstructive pulmonary disease.
I
Intervention
Chronic obstructive pulmonary disease (COPD) diagnosis
C
Comparator
Controls without chronic obstructive pulmonary disease
O
Outcome
Incident cases of a first myocardial infarction, lung cancer, hip fracture, depression, and diabetes mellitushard clinical
COPD is associated with a significantly increased risk of myocardial infarction and other major comorbidities, highlighting the need for comprehensive risk management in these patients.
Cite This Study
Sode et al. (2011) studied this question.