What question did this study set out to answer?

This review aims to explore the dual role of oxidative and reductive stress in myocardial ischemia and reperfusion injury, alongside potential therapies.

January 1, 2016Oxidative Medicine and Cellular LongevityOpen Access

The Role of Oxidative Stress in Myocardial Ischemia and Reperfusion Injury and Remodeling: Revisited

View Full Paper

Ask AI

Bookmark

Design

Review

Authors

GKGino A. KurianSASTRA University RRRashmi RajagopalSASTRA University SVSrinivasan VedanthamSASTRA University

Discussion

Member takes

Implication

Mitochondrial malfunction links oxidative and reductive stress via redox rheostat failure; leaves open targeted modulation in cardiovascular adaptation.

Key Points

This review aims to explore the dual role of oxidative and reductive stress in myocardial ischemia and reperfusion injury, alongside potential therapies.
Reviewed current experimental evidence on oxidative stress in major cardiovascular diseases.
Discussed mechanisms of mitochondrial dysfunction related to oxidative and reductive stress.
Proposed antioxidant drug therapy targeting subcellular organelles for cardiac conditions.
Outlined the critical role of oxidative stress in myocardial infarction and diabetic cardiovascular complications.
Highlight potential therapeutic interventions focusing on organelle-targeted antioxidants.
Emphasized the importance of addressing oxidative and reductive stress to improve myocardial health.

Cite This Study

Kurian et al. (2016) studied this question.

synapsesocial.com/papers/6a6f64c4f44fa9f079dcd30e https://doi.org/10.1155/2016/1656450

View Full Paper

Ask AI

Bookmark

Implication

Mitochondrial malfunction links oxidative and reductive stress via redox rheostat failure; leaves open targeted modulation in cardiovascular adaptation.

The Role of Oxidative Stress in Myocardial Ischemia and Reperfusion Injury and Remodeling: Revisited

Discussion

Member takes

Implication

Key Points

Cite This Study

The Role of Oxidative Stress in Myocardial Ischemia and Reperfusion Injury and Remodeling: Revisited

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider