Why the study?
Wearable devices only provide ECGs with a couple of leads, leading to inaccurate diagnosis of cardiac disease due to the lack of required leads.
Does a deep generative model synthesizing 12-lead ECGs from two asynchronous leads improve classification performance for myocardial infarction and arrhythmia compared to models using one or two leads?
Does a deep generative model synthesizing 12-lead ECGs from two asynchronous leads improve classification performance for myocardial infarction and arrhythmia compared to models using one or two leads?
A deep generative model can synthesize 12-lead ECGs from two asynchronous leads with high fidelity, improving downstream classification of myocardial infarction and arrhythmia compared to using only one or two leads.
Limited-lead wearables may broaden ECG access; leaves open whether diagnostic accuracy matches 12-lead standards.
The electrocardiogram (ECG) records electrical signals in a non-invasive way to observe the condition of the heart, typically looking at the heart from 12 different directions. Several types of the cardiac disease are diagnosed by using 12-lead ECGs Recently, various wearable devices have enabled immediate access to the ECG without the use of wieldy equipment. However, they only provide ECGs with a couple of leads. This results in an inaccurate diagnosis of cardiac disease due to lacking of required leads. We propose a deep generative model for ECG synthesis from two asynchronous leads to ten leads. It first represents a heart condition referring to two leads, and then generates ten leads based on the represented heart condition. Both the rhythm and amplitude of leads generated resemble those of the original ones, while the technique removes noise and the baseline wander appearing in the original leads. As a data augmentation method, our model improves the classification performance of models compared with models using ECGs with only one or two leads.
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Jo et al. (2021) studied this question.
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