Why the study?
Does high-resolution 7-Tesla cardiac MRI accurately quantify myocardial mass in a mouse model compared to ex vivo measurements?
Population
8 male mice
Comparison
High-resolution cardiac magnetic resonance imaging vs Ex vivo determination of left ventricular mass
Design
Preclinical
Authors
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Supports noninvasive LV mass quantification in mice; extends high-field MRI validation for preclinical studies but should not guide clinical practice.
Does high-resolution 7-Tesla cardiac MRI accurately quantify myocardial mass in a mouse model compared to ex vivo measurements?
High-resolution 7-Tesla cardiac MRI provides accurate and reproducible noninvasive quantification of left ventricular mass and function in mice.
Ruff et al. (1998) studied this question.
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