Demonstrates that a lack of respiratory modulation on venous ultrasound in suspected DVT should prompt further investigation for proximal compressive pathology such as malignancy.
Answers are grounded in this paper and cite their sources.
May prompt CT evaluation for malignancy when venous ultrasound shows absent respiratory modulation; single case report leaves open need for validation.
A 69-year-old woman presented to the emergency department (ED) with a swollen left thigh and leg. D-dimer test was positive, a radiology department ultrasound showed no direct evidence of a deep venous thrombosis but a lack of respiratory modulation was seen. ED ultrasound showed large groin lymph nodes and this, together with low haemoglobin, prompted a CT scan which led to the diagnosis of metastatic carcinoma.
No takes yet. Share an insight, caveat, or question.
Sharma et al. (2013) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: