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May 1, 1988Journal of Biological ChemistryOpen Access

1,2-Diacylglycerols, but not phorbol esters, activate a potential inhibitory pathway for protein kinase C in GH3 pituitary cells. Evidence for involvement of a sphingomyelinase.

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Authors

RKRichard KolesnickMemorial Sloan Kettering Cancer CenterSCS. CleggMemorial Sloan Kettering Cancer Center

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Kolesnick et al. (1988) studied this question.

synapsesocial.com/papers/6a6f6e68f44fa9f079dcde4ehttps://doi.org/10.1016/s0021-9258(18)68674-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 11,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cells.1987 · 209 citations
  2. 2Ca2+-binding proteins from bovine brain including a potent inhibitor of protein kinase C1985 · 93 citations
  3. 3Failure of 1-oleoyl-2-acetylglycerol to mimic the cell-differentiating action of 12-O-tetradecanoylphorbol 13-acetate in HL-60 cells.1985 · 123 citations
  4. 4Endogenous inhibitor of protein kinase C: association with human peripheral blood neutrophils but not with specific granule-deficient neutrophils or cytoplasts.1986 · 38 citations
  5. 5Structural requirements for diacylglycerols to mimic tumor-promoting phobol diester action on the epidermal growth factor receptor.1985 · 98 citations