Why the study?
Caudal block is preferred for pediatric surgery below the umbilicus, but comparative data evaluating bupivacaine with neostigmine versus bupivacaine alone on intraoperative hemodynamics and postoperative pain control were needed.
Does caudal block with bupivacaine plus neostigmine improve intraoperative hemodynamics and postoperative pain control in pediatrics undergoing lower abdominal surgery?
Does caudal block with bupivacaine plus neostigmine improve intraoperative hemodynamics and postoperative pain control in pediatrics undergoing lower abdominal surgery?
The addition of 2μg/kg neostigmine to caudal bupivacaine provides safe and effective postoperative analgesia for up to 24 hours in pediatric patients undergoing lower abdominal surgery.
Caudal block offers practical versatility for infraumbilical pediatric surgery; leaves open optimal technique comparisons in broader trials.
Background Peripheral nerve blocks provide prolonged analgesia restricted to the site of surgery e.g. penile block for circumcision or sciatic nerve block for pediatric surgery. The drawback is not all anesthesiologists are familiar with the necessary spectrum of peripheral nerve blocks in children. That is why Caudal block is preferred as all types of surgery below the umbilicus can be covered by it: ‘one technique fits all’. The main goal of caudal block is to provide postoperative pain relief, in addition it can be effective intraoperative and it is accepted that the block is performed in anesthetized children. Objectives The aim of this work is to compare Bupivacaine with Neostigmine and Bupivacaine alone as regard intraoperative hemodynamics and postoperative pain control for lower abdominal surgery in pediatrics. Patients and Methods Prospective randomized controlled clinical Trial. Conclusion In conclusion, caudal bupivacaine plus 2μg/kg neostigmine provided excellent analgesia lasting up to 24 hours post-operative, without serious side effects and minimal additional analgesics thus providing a safe, simple and effective postoperative analgesia for children undergoing lower abdominal surgery.
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Hassan et al. (2020) studied this question.
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