This report is an effort to summarize the most recent developments in antigens and serologic tests used for the diagnosis and prognosis of histoplasmosis, blastomycosis, coccidioidomycosis, paracoccidioidomycosis and cryptococcosis. Studies by means of immunodiffusion (ID) in agar gels (AG), viz.; various modifications of the procedure described by Ouchterlony, are emphasized. The absence of standardization in terminology of either this test—ID, AG or Ouchterlony—or the antigenic constituents reactive at different stages of the infections or diseases is perhaps representative of the confusion currently existing in the serologic study of the respiratory mycoses. Este informe es un intento de resumir los mas recientes trabajos sobre antígenos y pruebas serológicas usados para el diagnóstico y prognóstico de histoplasmosis, blastomicosis, coccidioidomicosis, paracoccidioidomicosis y cryptococcosis. Varias modificaciones al procedimiento descripto por Ouchterlony para immunodifusión (ID) en gel de agar (AG) son especialmente tratadas. La ausencia de standarizatíon, tanto en la terminología de estas pruebas—(ID) (AG) Ouchterlony—como en la existencia de áctivos componentes antigénicos a diferentes etapas de las micosis respiratoras, es talvez representativa de la confusíon existente en los estudios serológicos.
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Charlotte C. Campbell (1967) studied this question.
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