September 1, 1993Journal of Applied Physiology
Influence of active muscle size on sympathetic nerve discharge during isometric contractions in humans
Why the study?
Does active muscle size influence sympathetic nerve discharge and cardiovascular function during isometric contractions in humans?
Population
6 human subjects
Comparison
Isometric contractions of fore- and upper arm… vs Isometric contractions of a small hand muscle…
Design
Other
Authors
Discussion
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Implication
Muscle mass may modulate sympathetic and pressor responses during isometric exercise; hypothesis-generating and should not yet change practice.
Structured PICO
Does active muscle size influence sympathetic nerve discharge and cardiovascular function during isometric contractions in humans?
P
Population
6 human subjects
I
Intervention
Isometric contractions of fore- and upper arm muscles (handgrip) sustained to the point of exhaustion
C
Comparator
Isometric contractions of a small hand muscle (1st dorsal interosseus [FDI]) sustained to the point of exhaustion
O
Outcome
Sympathetic nerve discharge to nonactive skeletal muscle (MSNA)surrogate
Active muscle size is an important factor in regulating sympathetic nervous system discharge and cardiovascular function during isometric muscle activity.
Cite This Study
Douglas R. Seals (1993) studied this question.