In infants and children with paroxysmal ventricular tachycardia or fibrillation, underlying heart disease is common, and beta-blockers may be beneficial for those with brief malignant tachycardia.
Answers are grounded in this paper and cite their sources.
Beta-blockers may benefit select children with brief malignant tachycardia; hypothesis-generating and should not yet change practice in pediatric VT/VF.
Summary A retrospective 3–20‐years follow‐up study of 1 infant and 10 children with paroxysmal ventricular tachycardia (8 cases) or fibrillation (3 cases) is presented. Additional heart disease has been observed in 60% (myocarditis 3 cases, cardiomyopathy 3 cases, congenital heart disease 1 case). Symptoms of tachycardia were: palpitation, tiredness, weakness, dyspnoea, precordial and abdominal pain. Syncopes were observed in 3 cases; 1 child had no symptoms. Tachycardia of hours to days' duration have been noted in 8 patients, 7 had tachycardia of repetitive type with a‐v dissociation, one continuous tachycardia without any intervening sinus beats after the onset of tachycardia and with retrograde atrial activation. The remaining 3 children had brief malignant tachycardia, i.e. stress‐provoked bursts of ventricular activity occasionally converting to ventricular fibrillation causing syncope. The diagnosis of brief malignant tachycardia had to be based on exercise ECG (2 cases) or long‐term ECG‐monitoring by telemetry (one case). One child with cardiomyopathy had died at the time of follow‐up and the 3 patients with brief malignant tachycardia had experienced repeated life‐threatening attacks—one of which had to be stopped by emergency d.c. countershock. The period of attacks ceased in 5 cases within 2 years after onset, in 1 patient, 9 years elapsed between first and second attack. Preventive treatment with betablocking agents proved beneficial in the 3 children with brief malignant tachycardia.
No takes yet. Share an insight, caveat, or question.
Videbæk et al. (1973) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: