Intravenous adenosine used for PSVT termination may be associated with the development of non-sustained broad-complex tachycardia.
Adenosine use in PSVT should not change on this basis; single case leaves open incidence and clinical relevance.
Adenosine induces short-lived atrioventricular nodal (AVN) blockade when injected intravenously and has superceded verapamil as the drug of choice for the termination of re-entrant paroxysmal supraventricular tachycardias (PSVT).' It has also been found to be useful in the diagnosis of broad-complex tachycardia, distinguishing PSVT with aberrant conduction, which is terminated by adenosine, from pre- excited atrial arrhythmias and ventricular tachycardia (VT), which are not.This agent's excellent safety profile is, in part, a reflection of its short half-life and the more frequent side-effects of dyspnoea, flushing and chest pain are transient and well tolerated. Al- though rhythm disturbances (predominantly bradyarrhythmias) have been described, few serious arrhythmia complications have been documented. We report the observation of non-sustained broadcomplex tachycardia following intravenous adenosine for the treatment of PSVT.
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Hingorani et al. (1995) studied this question.
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