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October 1, 1975ThoraxOpen Access

Variability of routine pulmonary function tests.

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Population

Normal subjects, patients with stable irreversible airways obstruction, and patients with stable restrictive…

Design

Cohort

Authors

JHJán HrubýCzech Hydrometeorological InstituteJBJohn ButlerWestern University

Discussion

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Implication

Diurnal PFT variability may confound serial monitoring; leaves open optimal timing standardization for longitudinal studies.

Structured PICO

P
Population
Normal subjects, patients with stable irreversible airways obstruction, and patients with stable restrictive disease
I
Intervention
Repeated measurement of routine pulmonary function tests (VC, FEV1, FRC, and airway resistance)
O
Outcome
Diurnal and random variations in pulmonary function testssurrogate

Routine pulmonary function tests show significant diurnal and random variability, emphasizing the need to standardize testing times when assessing disease progression or therapy effects.

Cite This Study

Hrubý et al. (1975) studied this question.

synapsesocial.com/papers/6a6f77fff44fa9f079dcea6fhttps://doi.org/10.1136/thx.30.5.548
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Also Consider

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  1. 1Normal Standards for Lung Volumes, Intrapulmonary Gas-mixing, and Maximum Breathing Capacity1954 · 302 citations
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