What question did this study set out to answer?

This study aims to assess heart rate changes and the role of parasympathetic pathways following RF ablation of supraventricular tachycardia.

October 1, 1993Circulation

Alterations of heart rate and of heart rate variability after radiofrequency catheter ablation of supraventricular tachycardia. Delineation of parasympathetic pathways in the human heart.

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Why the study?

Does radiofrequency catheter ablation alter heart rate and heart rate variability in patients with supraventricular tachycardia?

Population

85 patients, comprising 64 patients with supraventricular tachycardia undergoing radiofrequency ablation and…

Comparison

Radiofrequency catheter ablation vs Diagnostic electrophysiology study without…

Design

Cohort

Follow-up

6 months

Authors

DKDusan Z. KocovicMain Line Health THTomoo HaradaSt. Marianna University School of Medicine JSJohn B. SheaIndiana University Bloomington

Discussion

Member takes

Implication

Transient HR/HRV changes after AV nodal ablation warrant no practice change; leaves open mechanisms and long-term implications in prospective studies.

Key Points

This study aims to assess heart rate changes and the role of parasympathetic pathways following RF ablation of supraventricular tachycardia.
Conducted time and frequency domain analysis of heart rate in 64 patients before and after RF ablation.
Compared data from 21 control patients undergoing diagnostic study without ablation.
Analyzed ambulatory Holter monitor data at 1 day, 1 month, and 6 months post-ablation.
Mean heart rate increased significantly post-ablation for specific pathways, indicating changes in heart rhythm.
Heart rate variability decreased significantly as measured by SD, MSSD, and PNN50 immediately after ablation.
High frequency component analysis showed a marked reduction, suggesting parasympathetic denervation.

Structured PICO

Does radiofrequency catheter ablation alter heart rate and heart rate variability in patients with supraventricular tachycardia?

Population

85 patients, comprising 64 patients with supraventricular tachycardia undergoing radiofrequency ablation (fast AV nodal pathway n=3, slow AV nodal pathway n=14, posteroseptal accessory pathway n=23, left lateral accessory pathway n=24) and 21 control patients undergoing diagnostic study without ablation.

Intervention

Radiofrequency catheter ablation

Comparator

Diagnostic electrophysiology study without ablation

Outcome

Changes in heart rate and heart rate variability (time and frequency domain analysis) immediately before and after the proceduresurrogate

Radiofrequency ablation near the low interatrial septum causes transient parasympathetic denervation, leading to acute increases in heart rate and reduced heart rate variability that resolve within 1 to 6 months.

Cite This Study

Kocovic et al. (1993) studied this question.

synapsesocial.com/papers/6a6f781053da1ffdb5079044 https://doi.org/10.1161/01.cir.88.4.1671

Topics

AF ablation outcomes

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Implication

Transient HR/HRV changes after AV nodal ablation warrant no practice change; leaves open mechanisms and long-term implications in prospective studies.

Alterations of heart rate and of heart rate variability after radiofrequency catheter ablation of supraventricular tachycardia. Delineation of parasympathetic pathways in the human heart.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Alterations of heart rate and of heart rate variability after radiofrequency catheter ablation of supraventricular tachycardia. Delineation of parasympathetic pathways in the human heart.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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