Temporo-spatial stability of complex fractionated atrial electrograms in two distinct and separate episodes of paroxysmal atrial fibrillation

D. Redfearn; C.S. Simpson; Hoshiar Abdollah; A. Baranchuk

doi:10.1093/europace/eup287

October 30, 2009EP Europace

Temporo-spatial stability of complex fractionated atrial electrograms in two distinct and separate episodes of paroxysmal atrial fibrillation

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Why the study?

Does the temporo-spatial distribution of complex fractionated atrial electrograms remain stable across two distinct episodes of paroxysmal atrial fibrillation?

Structured PICO

Does the temporo-spatial distribution of complex fractionated atrial electrograms remain stable across two distinct episodes of paroxysmal atrial fibrillation?

P

Population

10 patients with paroxysmal atrial fibrillation (mean age 59.5 years, 3 female)

I

Intervention

Repeat left atrial mapping using the EnSite system during a second episode of atrial fibrillation (re-induced after electrical cardioversion and 10 minutes of sinus rhythm)

C

Comparator

Initial left atrial mapping during the first episode of induced or spontaneous atrial fibrillation

O

Outcome

Temporo-spatial reproducibility of complex fractionated atrial electrograms (CFAE) between the two episodes, assessed by comparing mean cycle length at identical verticessurrogate

Complex fractionated atrial electrograms demonstrate high temporo-spatial reproducibility across separate episodes of paroxysmal atrial fibrillation, supporting their potential as stable targets for ablation.