This review discusses the pathophysiological role of the renal nerves in sympathetic hyperactivity and the potential therapeutic role of catheter-based renal denervation.
Recently, catheter-based renal denervation (RDN) has become available. In order to understand better the possible role of RDN as a treatment modality, we first discuss the anatomy and function of the renal nerves in this brief review. Secondly, we address the question - what is the clinical evidence for the involvement of the kidneys and renal nerves in the pathogenesis of sympathetic hyperactivity. Finally, we will discuss how this sympathetic hyperactivity can be reduced, specifically addressing the possible role of RDN.
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Jager et al. (2013) studied this question.
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