What question did this study set out to answer?

To evaluate cardiac changes in patients with chronic renal failure before and after renal transplantation.

February 1, 1982HeartOpen Access

Effects of renal transplantation on left ventricular size and function.

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Why the study?

Does successful renal transplantation improve left ventricular size and function in patients with chronic renal failure and uraemia?

Population

13 patients with chronic renal failure and uraemia

Comparison

Successful renal transplantation vs Preoperative state

Design

Case_series

Authors

MIMarkku J. IkäheimoOulu University Hospital MLMarkku LinnaluotoOulu University Hospital KHK HuttunenOulu University Hospital

Discussion

Member takes

Implication

May lessen LV hypertrophy after renal transplant in uremia; hypothesis-generating and needs prospective confirmation before practice change.

Key Points

To evaluate cardiac changes in patients with chronic renal failure before and after renal transplantation.
Investigated 13 patients with chronic renal failure via echocardiography preoperatively, post-haemodialysis, and after renal transplantation.
Measured left ventricular diameters, wall thickness, mass, and cardiac index.
Left ventricular end-diastolic and end-systolic diameters decreased post-transplantation.
Left atrial diameter also reduced due to decreased left ventricular preload.
Renal transplantation reduced left ventricular hypertrophy without significantly improving function.

Structured PICO

Does successful renal transplantation improve left ventricular size and function in patients with chronic renal failure and uraemia?

Population

13 patients with chronic renal failure and uraemia

Intervention

Successful renal transplantation

Comparator

Preoperative state (before and after haemodialysis)

Outcome

Cardiac changes (left ventricular size and function) evaluated by echocardiographysurrogate

Successful renal transplantation in patients with chronic renal failure reduces left ventricular hypertrophy and normalizes cardiac volumes, though it does not significantly improve intrinsic left ventricular function.

Cite This Study

Ikäheimo et al. (1982) studied this question.

synapsesocial.com/papers/6a6f7bb8ac440176ef2828b5 https://doi.org/10.1136/hrt.47.2.155

Topics

Echocardiography

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Implication

May lessen LV hypertrophy after renal transplant in uremia; hypothesis-generating and needs prospective confirmation before practice change.

Effects of renal transplantation on left ventricular size and function.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Effects of renal transplantation on left ventricular size and function.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider