Why the study?
Cardiac involvement reports in FSHD1 are conflicting, and it remains unknown whether subclinical cardiac involvement is detectable using CMR in patients with preserved left ventricular systolic function.
Does cardiovascular magnetic resonance detect subclinical myocardial injury in patients with Facioscapulohumeral muscular dystrophy 1 and preserved ejection fraction compared to healthy controls?
Does cardiovascular magnetic resonance detect subclinical myocardial injury in patients with Facioscapulohumeral muscular dystrophy 1 and preserved ejection fraction compared to healthy controls?
Patients with FSHD1 and preserved LVEF exhibit subclinical focal and diffuse myocardial injury detectable by CMR, highlighting the potential need for early cardiac monitoring in this population.
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Subclinical myocardial injury appears detectable in FSHD1 with preserved EF; prospective studies needed to clarify prognostic relevance.
Błaszczyk et al. (2019) studied this question.
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