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April 1, 1993American Journal of Hematology

Viridans streptococcal shock in bone marrow transplantation patients

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Population

832 patients receiving a bone marrow transplant at the University of Minnesota between 1976 and 1988…

Design

Cohort

Authors

MSMarie E. SteinerBoston UniversityJVJudith G. VillablancaUniversity of Southern CaliforniaJKJohn KerseyIndiana University Health

Discussion

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Implication

May warrant age-stratified monitoring in neutropenic transplant recipients with viridans streptococcal bacteremia; leaves open prospective validation of pediatric risk.

Structured PICO

P
Population
832 patients receiving a bone marrow transplant at the University of Minnesota between 1976 and 1988, including 123 with viridans streptococcal bacteremia and 10 who developed clinical shock.
O
Outcome
Development of clinical shock and mortality associated with viridans streptococcal sepsishard clinical

Viridans streptococcal bacteremia can cause a rapidly progressive, often fatal shock syndrome in neutropenic bone marrow transplant patients, particularly in those younger than 15 years.

Cite This Study

Steiner et al. (1993) studied this question.

synapsesocial.com/papers/6a6f8a6775498292b708eb83https://doi.org/10.1002/ajh.2830420405
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Pathogenesis of Sepsis1991 · 1,375 citations
  2. 2Therapy of severe aplastic anemia in young adults and children with allogeneic bone marrow transplantation1987 · 58 citations
  3. 3Septicemia in pediatric oncology patients: the significance of viridans streptococcal infections.1990 · 92 citations
  4. 4Therapy of severe aplastic anemia in young adults and children with allogeneic bone marrow transplantation1987 · 61 citations