TREATMENT It was but part of a natural course of events which caused irradiation to supplant surgical methods almost entirely in the treatment of lymphosarcoma, for in no other tumor process is there so startling a response to this mode of therapy. In general lymphosarcoma is extremely radiosensitive, and it is not surprising to observe a bulky tumor mass regress to half its size after a few days of treatment and completely disappear within a week. Recurrences in areas adequately treated rarely occur, the new evidence of disease being found elsewhere. With several types of irradiation available at the Memorial Hospital, various methods of treatment and their combinations have been employed over a twenty year period. Forty-nine per cent of the patients were treated by x-rays alone generated at from 140 to 200 kilovolts. Target-skin distances varied from 35 to 100 cm., depending on the depth of the tumor beneath
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Sugarbaker et al. (1940) studied this question.