Key result
Higher monocyte-to-HDL ratio linked to ~8 mm larger abdominal aortic aneurysm diameter.
Observational (n=120)
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AIM: To determine the association of monocyte count-to-high-density lipoprotein (HDL)-cholesterol ratio, a recently emerged inflammatory marker, with abdominal aortic aneurysm (AAA) size. PATIENTS & METHODS: A total of 120 asymptomatic AAA subjects (99 male, mean age: 67.1 ± 10.2 years) were enrolled into the study. All data were compared between patients with low and high admission monocyte/HDL ratio. Multivariate linear regression analysis was performed to study the relationship between different variables and AAA size. RESULTS: Compared to patients with below-median monocyte/HDL ratio, aneurysm diameter was significantly higher in above-median monocyte/HDL ratio group (54.3 ± 10.6 mm vs 62.0 ± 12.4 mm, p < 0.001, respectively). Hypertension, coronary artery disease, monocyte/HDL ratio and C-reactive protein were independently associated with AAA diameter. CONCLUSION: Monocyte/HDL ratio is independently associated with AAA size.
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Çağlı et al. (2016) conducted an observational in Abdominal Aortic Aneurysm (AAA) (n=120). Above-median monocyte-to-HDL ratio vs. Below-median monocyte-to-HDL ratio was evaluated on Abdominal aortic aneurysm (AAA) diameter (p=<0.001). An above-median monocyte-to-HDL ratio was associated with a significantly larger abdominal aortic aneurysm diameter compared to a below-median ratio (62.0 mm vs 54.3 mm, P<0.001).
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