Genetic Homology Between Escherichia Coli K-12 and Salmonella

Falkow, Stanley (Walter Reed Army Institute of Research, Washington, D.C.), Robert Rownd, and L. S. Baron. Genetic homology between Escherichia coli K-12 and Salmonella. J. Bacteriol. 84:1303-1312. 1962.-Recombinant analysis and interrupted mating procedures, in conjunction with molecular hybridization experiments, demonstrated that the genetic homology between Escherichia and Salmonella is incomplete. The most likely explanation of this incomplete homology is imperfect pairing between the deoxyribonucleic acid molecules of the two species. Despite the inhomologies, there is ample evidence that the order and distance of the genetic characters on the Salmonella chromosome are identical to those of Escherichia.