Why the study?
Noninvasive detection of functionally significant CAD by echocardiography remains challenging and usually requires stress imaging. The authors investigated whether resting global myocardial work could predict significant CAD in patients with preserved LVEF and no regional wall motion abnormalities.
Does global myocardial work predict significant coronary artery disease better than global longitudinal strain in patients with normal left ventricular function?
Comparison
Global myocardial work vs global longitudinal strain
Design
Diagnostic observational study
Authors
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Global MW at rest may identify significant CAD without wall motion abnormalities; hypothesis-generating and requires prospective validation before practice change.
Does global myocardial work predict significant coronary artery disease better than global longitudinal strain in patients with normal left ventricular function?
Noninvasive global myocardial work at rest is superior to global longitudinal strain for detecting significant CAD in patients with normal LV function and no regional wall motion abnormalities.
Edwards et al. (2019) studied this question.
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