What question did this study set out to answer?

To achieve sub-micron spatial resolution across a large imaging field-of-view using lensfree on-chip holographic microscopy and pixel super-resolution.

May 12, 2010Optics ExpressOpen Access

Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution

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Authors

WBWaheb Bishara TSTing‐Wei Su ACAhmet F. Coskun

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Overview

Experimental study demonstrates high-resolution lensfree on-chip microscopy across a wide field of view, suggesting cost-effective high-throughput imaging.

Key Points

To achieve sub-micron spatial resolution across a large imaging field-of-view using lensfree on-chip holographic microscopy and pixel super-resolution.
Captured lower-resolution in-line holograms of samples using partially coherent light emitted from an approximately 50 µm aperture with unit fringe magnification.
Implemented a sub-pixel shifting based super-resolution algorithm to reconstruct high-resolution digital holograms by overcoming the physical pixel size limits of the sensor chip.
Tested the platform using patterned transparent substrates, blood smear samples, and Caenorhabditis elegans.
Achieved a spatial resolution of approximately 0.6 µm, corresponding to a numerical aperture of approximately 0.5.
Maintained sub-micron resolution across an entire sensor active area and field-of-view of approximately 24 mm².

Cite This Study

Bishara et al. (2010) studied this question.

synapsesocial.com/papers/6a6f93d9fe4101aa97dfd60a https://doi.org/10.1364/oe.18.011181

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May 12, 2010Optics ExpressOpen Access

Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution

View Full Paper

Ask AI

Bookmark

Authors

WBWaheb Bishara TSTing‐Wei Su ACAhmet F. Coskun

Discussion

Member takes

Overview

Experimental study demonstrates high-resolution lensfree on-chip microscopy across a wide field of view, suggesting cost-effective high-throughput imaging.

Key Points

To achieve sub-micron spatial resolution across a large imaging field-of-view using lensfree on-chip holographic microscopy and pixel super-resolution.
Captured lower-resolution in-line holograms of samples using partially coherent light emitted from an approximately 50 µm aperture with unit fringe magnification.
Implemented a sub-pixel shifting based super-resolution algorithm to reconstruct high-resolution digital holograms by overcoming the physical pixel size limits of the sensor chip.
Tested the platform using patterned transparent substrates, blood smear samples, and Caenorhabditis elegans.
Achieved a spatial resolution of approximately 0.6 µm, corresponding to a numerical aperture of approximately 0.5.
Maintained sub-micron resolution across an entire sensor active area and field-of-view of approximately 24 mm².

Cite This Study

Bishara et al. (2010) studied this question.

synapsesocial.com/papers/6a6f93d9fe4101aa97dfd60a https://doi.org/10.1364/oe.18.011181

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