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A syncytial giant cell (SGC) focus assay for feline leukemia and simian sarcoma virus preparations has been developed. This assay is based on the cytopathogenic reaction that appears in cultures where XC cells are overlayed on virus infected M.132-1 cells. Results of titrations of virus stocks were determined in a period of 1 wk by the use of the SGC focus method. SGC focus formation was prevented when the test virus was reacted with specific antisera.
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Rangan et al. (1973) studied this question.
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