The trihalomethane (THM) yield on a total organic carbon basis was measured as a function of the molecular weight of precursor organics in the Iowa River. Gel permeation chromatography with Sephadex G-75 gel was utilized to separate naturally occurring organics into apparent molecular weight fractions that were subsequently chlorinated to 2 mg/L of free residual and analyzed for THMs.
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Schnoor et al. (1979) studied this question.