Insights from preclinical ultra high-density electroanatomical sinus node mapping
Population
14 anaesthetized and ventilated pigs
Comparison
Ultra high-density electroanatomical mapping of… vs Baseline mapping and comparison between…
Design
Preclinical
Authors
Discussion
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Implication
Animal findings on sinus node shifts should not change practice; hypothesis-generating for human validation of ultra-high-density mapping.
Structured PICO
P
Population
14 anaesthetized and ventilated pigs
I
Intervention
Ultra high-density electroanatomical mapping of the right atrium using the Rhythmia™ mapping system, including mapping after infusion of orciprenaline, propranolol, or amiodarone
C
Comparator
Baseline mapping (before drug infusion) and comparison between endocardial and epicardial mapping
O
Outcome
Identification of right atrial geometry, activation patterns, earliest activation sites (EAS), and sinus break-out (SBO)surrogate
Ultra high-density mapping using the Rhythmia system allows detailed assessment of sinus node activation and its shifts under pharmacological influence in a porcine model.
Cite This Study
Bollmann et al. (2014) studied this question.