September 1, 2008Journal of Trauma and Acute Care Surgery

Cardiac Uncoupling and Heart Rate Variability are Associated With Intracranial Hypertension and Mortality: A Study of 145 Trauma Patients With Continuous Monitoring

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Why the study?

Is cardiac uncoupling (low heart rate variability) associated with intracranial hypertension and mortality in trauma patients?

Population

145 trauma patients requiring intracranial monitoring with simultaneous heart rate variability and…

Design

Cohort

Authors

NMNathan T. MoweryThe Ohio State University PNPatrick R. NorrisFundación Juan March WRWilliam P. RiordanChristopher Newport University

Discussion

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Implication

Cardiac uncoupling may signal intracranial hypertension in trauma; hypothesis-generating and should not yet change monitoring practice.

Structured PICO

Is cardiac uncoupling (low heart rate variability) associated with intracranial hypertension and mortality in trauma patients?

Population

145 trauma patients requiring intracranial monitoring with simultaneous heart rate variability (HRV) and intracranial pressure (ICP) monitoring, from a larger cohort of 14,330 consecutive trauma admissions.

Intervention

Continuous monitoring of heart rate variability (assessing cardiac uncoupling, defined as standard deviation of heart rate between 0.3 bpm and 0.6 bpm over 5-minute intervals).

Outcome

Association between cardiac uncoupling (low HRV) and increases in intracranial pressure (ICP).surrogate

Cardiac uncoupling (low heart rate variability) is significantly associated with increased intracranial pressure and mortality in trauma patients, highlighting its potential as a noninvasive marker for intracranial hypertension.

Cite This Study

Mowery et al. (2008) studied this question.

synapsesocial.com/papers/6a6f97d28031ec7bb1dbd76d https://doi.org/10.1097/ta.0b013e3181837980

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Cardiac Uncoupling and Heart Rate Variability are Associated With Intracranial Hypertension and Mortality: A Study of 145 Trauma Patients With Continuous Monitoring

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Cardiac Uncoupling and Heart Rate Variability are Associated With Intracranial Hypertension and Mortality: A Study of 145 Trauma Patients With Continuous Monitoring

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider