Why the study?
Does steroid administration improve heart rate variability in critically ill trauma patients with adrenal insufficiency?
Population
1,871 critically ill trauma ICU patients
Comparison
Steroid administration vs Pre-steroid baseline and non-adrenal…
Design
Cohort
Follow-up
72 hours post-steroid administration
Authors
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HRVi may identify steroid responders among trauma ICU patients; hypothesis-generating and should not yet change practice.
Does steroid administration improve heart rate variability in critically ill trauma patients with adrenal insufficiency?
Reduced heart rate variability is associated with adrenal insufficiency in trauma ICU patients and improves in survivors responding to steroid therapy, suggesting its utility as a real-time biomarker.
Morris et al. (2007) studied this question.
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